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Bile acids are synthesized from cholesterol in the liver and are excreted into the duodenum where they are reabsorbed and metabolized. Seven bile acids have been identified. Four of these (cholic acid, deoxycholic acid, chenodeoxycholic acid, and cholic acid glycine conjugate) occur in free and conjugated forms. All bile acids (except glycocholic acid) are sulfated. Primary conjugation occurs with glycine, taurine, or taurocholic acid in order of decreasing efficiency. This conjugation leads to a terminal 7 alpha-hydroxyl group in position C-7. Secondary conjugation can occur with steroid or phenol derivatives, but the exact pathways are not fully elucidated. Both conjugation steps are catalyzed by UDP-glucuronosyltransferases in the liver. The substrate specificities of these enzymes are very similar to those of the family of UDP-glucuronosyltransferases that have a broad substrate specificity, but that have been shown to be very specific for steroid hormones (i.e., glucuronidation can occur at C-6, C-16 and C-17 but cannot occur at C-7, C-18 or C-19). The process of bile acid conjugation is regulated in such a way that bile acid concentrations in the plasma or in the gallbladder should be kept at certain, specific levels. This regulation is achieved by the secretion of bile acids into the gut where these acids are reabsorbed and catabolized.

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Nfpa 70e – enp.pdf – Hack Generator Crack Wordpress – 3dGag.com. UNPUBLISHED

UNITED STATES COURT OF APPEALS
FOR THE FOURTH CIRCUIT

No. 05-2161

JOSE RAMOS-HERNANDEZ,

Petitioner,

versus

ALBERTO R. GONZALES, Attorney General,

Respondent.

On Petition for Review of an Order of the Board of Immigration
Appeals. (A97-782-256)

Submitted: February 16, 2006 Decided: March 24, 2006

Before NIEMEYER, WILLIAMS, and KING, Circuit Judges.

Petition denied by unpublished per curiam opinion.

Marc Van Der Hout, HOGAN & HARTSON, L.L.P., Arlington, Virginia,
for Petitioner. Peter D. Keisler, Assistant Attorney General,
Carol Federighi, Senior Litigation Counsel, Lindsay Corliss,
OFFICE OF IMMIGRATION LITIGATION, Washington, D.C., for Respondent.

Unpublished opinions are not binding precedent in this circuit.
See Local Rule 36(c).
PER CURIAM:
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